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mTOR may interact with PARP-1 to regulate visible light-induced parthanatos in photoreceptors
BACKGROUND: Excessive light exposure is a detrimental environmental factor that plays a critical role in the pathogenesis of retinal degeneration. However, the mechanism of light-induced death of retina/photoreceptor cells remains unclear. The mammalian/mechanistic target of rapamycin (mTOR) and Pol...
Autores principales: | Pan, Yi-Ran, Song, Jing-Yao, Fan, Bin, Wang, Ying, Che, Lin, Zhang, Si-Ming, Chang, Yu-Xin, He, Chang, Li, Guang-Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025415/ https://www.ncbi.nlm.nih.gov/pubmed/32066462 http://dx.doi.org/10.1186/s12964-019-0498-0 |
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