Celastrol Suppresses Glioma Vasculogenic Mimicry Formation and Angiogenesis by Blocking the PI3K/Akt/mTOR Signaling Pathway

Angiogenesis and vasculogenic mimicry (VM) are thought to be the predominant processes ensuring tumor blood supply during the growth and metastasis of glioblastoma (GBM). Celastrol has potential anti-glioma effects, however the mechanisms underlying these effects remain unclarified. Recent studies h...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yingjun, Liu, Xihong, Zhao, Peiyuan, Zhao, Hui, Gao, Wei, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025498/
https://www.ncbi.nlm.nih.gov/pubmed/32116702
http://dx.doi.org/10.3389/fphar.2020.00025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025498/
https://www.ncbi.nlm.nih.gov/pubmed/32116702
http://dx.doi.org/10.3389/fphar.2020.00025

Ejemplares similares