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Hypoxia influences polysome distribution of human ribosomal protein S12 and alternative splicing of ribosomal protein mRNAs

Ribosomes were once considered static in their composition because of their essential role in protein synthesis and kingdom-wide conservation. The existence of tolerated mutations in select ribosomal proteins (RPs), such as in Diamond-Blackfan anemia, is evidence that not all ribosome components are...

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Detalles Bibliográficos
Autores principales: Brumwell, Andrea, Fell, Leslie, Obress, Lindsay, Uniacke, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025504/
https://www.ncbi.nlm.nih.gov/pubmed/31911497
http://dx.doi.org/10.1261/rna.070318.119