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Cortical and Striatal Circuits in Huntington’s Disease

Huntington’s disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms. The disease is caused by a CAG triplet expansion in exon 1 of the huntingtin gene and leads to a severe neurodegeneration in the striatum and c...

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Detalles Bibliográficos
Autores principales: Blumenstock, Sonja, Dudanova, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025546/
https://www.ncbi.nlm.nih.gov/pubmed/32116525
http://dx.doi.org/10.3389/fnins.2020.00082