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Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells

Aging, noise, and ototoxic drug-induced hair cell (HC) loss are the major causes of sensorineural hearing loss. Aminoglycoside antibiotics are commonly used in the clinic, but these often have ototoxic side effects due to the accumulation of oxygen-free radicals and the subsequent induction of HC ap...

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Detalles Bibliográficos
Autores principales: Gao, Song, Cheng, Cheng, Wang, Maohua, Jiang, Pei, Zhang, Liyan, Wang, Ya, Wu, Huihui, Zeng, Xuanfu, Wang, Hui, Gao, Xia, Ma, Yongming, Chai, Renjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025583/
https://www.ncbi.nlm.nih.gov/pubmed/32116554
http://dx.doi.org/10.3389/fncel.2019.00590