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Intracochlear Perfusion of Tumor Necrosis Factor-Alpha Induces Sensorineural Hearing Loss and Synaptic Degeneration in Guinea Pigs
Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that plays a prominent role in the nervous system, mediating a range of physiologic and pathologic functions. In the auditory system, elevated levels of TNF-α have been implicated in several types of sensorineural hearing loss, includ...
Autores principales: | Katsumi, Sachiyo, Sahin, Mehmet I., Lewis, Rebecca M., Iyer, Janani S., Landegger, Lukas D., Stankovic, Konstantina M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025643/ https://www.ncbi.nlm.nih.gov/pubmed/32116980 http://dx.doi.org/10.3389/fneur.2019.01353 |
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