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Vancomycin concentrations in the cervical spine after intravenous administration: results from an experimental pig study

Background and purpose — Vancomycin may be an important drug for intravenous perioperative antimicrobial prophylaxis in spine surgery. We assessed single-dose vancomycin intervertebral disc, vertebral cancellous bone, and subcutaneous adipose tissue concentrations using microdialysis in a pig model....

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Detalles Bibliográficos
Autores principales: Bue, Mats, Hanberg, Pelle, Tøttrup, Mikkel, Thomassen, Maja B, Birke-Sørensen, Hanne, Thillemann, Theis M, Andersson, Torben L, Søballe, Kjeld
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025694/
https://www.ncbi.nlm.nih.gov/pubmed/30080983
http://dx.doi.org/10.1080/17453674.2018.1501548