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Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability

The numerous neurons and glia that form the brain originate from tightly controlled growth and division of neural stem cells, regulated systemically by important known stem cell-extrinsic signals. However, the cell-intrinsic mechanisms that control the distinctive proliferation rates of individual n...

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Detalles Bibliográficos
Autores principales: Samuels, Tamsin J, Järvelin, Aino I, Ish-Horowicz, David, Davis, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025822/
https://www.ncbi.nlm.nih.gov/pubmed/31934860
http://dx.doi.org/10.7554/eLife.51529