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Cryo-EM Structures of the Ionotropic Glutamate Receptor GluD1 Reveal a Non-Swapped Architecture

Ionotropic orphan delta receptors (GluD) are not gated by glutamate or any other endogenous ligand but are grouped with ionotropic glutamate receptors based on sequence similarity. GluD1 receptors play critical roles in synaptogenesis, synapse maintenance and have been implicated in neuronal disorde...

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Detalles Bibliográficos
Autores principales: Burada, Ananth Prasad, Vinnakota, Rajesh, Kumar, Janesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025878/
https://www.ncbi.nlm.nih.gov/pubmed/31925409
http://dx.doi.org/10.1038/s41594-019-0359-y