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Cryo-EM Structures of the Ionotropic Glutamate Receptor GluD1 Reveal a Non-Swapped Architecture
Ionotropic orphan delta receptors (GluD) are not gated by glutamate or any other endogenous ligand but are grouped with ionotropic glutamate receptors based on sequence similarity. GluD1 receptors play critical roles in synaptogenesis, synapse maintenance and have been implicated in neuronal disorde...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025878/ https://www.ncbi.nlm.nih.gov/pubmed/31925409 http://dx.doi.org/10.1038/s41594-019-0359-y |