Cargando…
Patterns of somatic structural variation in human cancer genomes
A key mutational process in cancer is structural variation, in which rearrangements delete, amplify or reorder genomic segments that range in size from kilobases to whole chromosomes(1–7). Here we develop methods to group, classify and describe somatic structural variants, using data from the Pan-Ca...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025897/ https://www.ncbi.nlm.nih.gov/pubmed/32025012 http://dx.doi.org/10.1038/s41586-019-1913-9 |