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1,25-dihydroxy Vitamin D3 and Interleukin-6 Blockade Synergistically Regulate Rheumatoid Arthritis by Suppressing Interleukin-17 Production and Osteoclastogenesis

BACKGROUND: Immune cells express the vitamin (vit) D receptor, and vit D is a potent immune-modulator. A negative correlation between serum vit D levels and rheumatoid arthritis (RA) disease activity has been reported. Therefore, we aimed to investigate if the sufficient serum vit D level is helpful...

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Detalles Bibliográficos
Autores principales: Kim, Haneul, Baek, Seungye, Hong, Seung-Min, Lee, Jaeseon, Jung, Seung Min, Lee, Jennifer, Cho, Mi-La, Kwok, Seung-Ki, Park, Sung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025907/
https://www.ncbi.nlm.nih.gov/pubmed/32056400
http://dx.doi.org/10.3346/jkms.2020.35.e40