Correlation of age-of-onset of Atopic Dermatitis with Filaggrin loss-of-function variant status

The genetic background of Atopic Dermatitis (AD) with chronic pruritus is complex. Filaggrin (FLG) is an essential gene in the epidermal barrier formation s. Loss-of-function (LOF) variants in FLG associated with skin barrier dysfunction constitute the most well-known genetic risk factor for AD. In...

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Detalles Bibliográficos
Autores principales: Smieszek, S. P., Welsh, S., Xiao, C., Wang, J., Polymeropoulos, C., Birznieks, G., Polymeropoulos, M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026049/
https://www.ncbi.nlm.nih.gov/pubmed/32066784
http://dx.doi.org/10.1038/s41598-020-59627-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026049/
https://www.ncbi.nlm.nih.gov/pubmed/32066784
http://dx.doi.org/10.1038/s41598-020-59627-7

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