Cognition- and circuit-based dysfunction in a mouse model of 22q11.2 microdeletion syndrome: effects of stress

Genetic microdeletion at the 22q11 locus is associated with very high risk for schizophrenia. The 22q11.2 microdeletion (Df(h22q11)/+) mouse model shows cognitive deficits observed in this disorder, some of which can be linked to dysfunction of the prefrontal cortex (PFC). We used behavioral (n = 10...

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Detalles Bibliográficos
Autores principales: Tripathi, Anushree, Spedding, Michael, Schenker, Esther, Didriksen, Michael, Cressant, Arnaud, Jay, Therese M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026063/
https://www.ncbi.nlm.nih.gov/pubmed/32066701
http://dx.doi.org/10.1038/s41398-020-0687-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026063/
https://www.ncbi.nlm.nih.gov/pubmed/32066701
http://dx.doi.org/10.1038/s41398-020-0687-z

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