Cargando…

Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma

Homologous recombination repair (HRR) pathway deficiency (HRD) is involved in the tumorigenesis and progression of high-grade serous ovarian carcinoma (HGSOC) as well as in the sensitivity to platinum chemotherapy drugs. In this study, we obtained data from The Cancer Genome Atlas (TCGA) on HGSOC an...

Descripción completa

Detalles Bibliográficos
Autores principales: Takaya, Hisamitsu, Nakai, Hidekatsu, Takamatsu, Shiro, Mandai, Masaki, Matsumura, Noriomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026096/
https://www.ncbi.nlm.nih.gov/pubmed/32066851
http://dx.doi.org/10.1038/s41598-020-59671-3