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Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma
Homologous recombination repair (HRR) pathway deficiency (HRD) is involved in the tumorigenesis and progression of high-grade serous ovarian carcinoma (HGSOC) as well as in the sensitivity to platinum chemotherapy drugs. In this study, we obtained data from The Cancer Genome Atlas (TCGA) on HGSOC an...
Autores principales: | Takaya, Hisamitsu, Nakai, Hidekatsu, Takamatsu, Shiro, Mandai, Masaki, Matsumura, Noriomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026096/ https://www.ncbi.nlm.nih.gov/pubmed/32066851 http://dx.doi.org/10.1038/s41598-020-59671-3 |
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