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Long Term Gene Expression in Human Induced Pluripotent Stem Cells and Cerebral Organoids to Model a Neurodegenerative Disease

Human brain organoids (mini-brains) consist of self-organized three-dimensional (3D) neural tissue which can be derived from reprogrammed adult cells and maintained for months in culture. These 3D structures manifest substantial potential for the modeling of neurodegenerative diseases and pave the w...

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Detalles Bibliográficos
Autores principales: Nassor, Ferid, Jarray, Rafika, Biard, Denis S. F., Maïza, Auriane, Papy-Garcia, Dulce, Pavoni, Serena, Deslys, Jean-Philippe, Yates, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026130/
https://www.ncbi.nlm.nih.gov/pubmed/32116560
http://dx.doi.org/10.3389/fncel.2020.00014