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Variability in estimated gene expression among commonly used RNA-seq pipelines
RNA-sequencing data is widely used to identify disease biomarkers and therapeutic targets using numerical methods such as clustering, classification, regression, and differential expression analysis. Such approaches rely on the assumption that mRNA abundance estimates from RNA-seq are reliable estim...
Autores principales: | Arora, Sonali, Pattwell, Siobhan S., Holland, Eric C., Bolouri, Hamid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026138/ https://www.ncbi.nlm.nih.gov/pubmed/32066774 http://dx.doi.org/10.1038/s41598-020-59516-z |
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