Silibinin Augments the Antifibrotic Effect of Valsartan Through Inactivation of TGF-β1 Signaling in Kidney

BACKGROUND: Chronic kidney disease (CKD) has become a major public health issue. Meanwhile, renal fibrosis caused by diabetic nephropathy can lead to CKD, regardless of the initial injury. It has been previously reported that silibinin or valsartan could relieve the severity of renal fibrosis. Howev...

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Detalles Bibliográficos
Autores principales: Liu, Ronggui, Wang, Qinqin, Ding, Zhaoyan, Zhang, Xiaojuan, Li, Yunping, Zang, Yichen, Zhang, Guijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026148/
https://www.ncbi.nlm.nih.gov/pubmed/32103902
http://dx.doi.org/10.2147/DDDT.S224308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026148/
https://www.ncbi.nlm.nih.gov/pubmed/32103902
http://dx.doi.org/10.2147/DDDT.S224308

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