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The Ca(2+) permeation mechanism of the ryanodine receptor revealed by a multi-site ion model

Ryanodine receptors (RyR) are ion channels responsible for the release of Ca(2+) from the sarco/endoplasmic reticulum and play a crucial role in the precise control of Ca(2+) concentration in the cytosol. The detailed permeation mechanism of Ca(2+) through RyR is still elusive. By using molecular dy...

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Detalles Bibliográficos
Autores principales: Zhang, Aihua, Yu, Hua, Liu, Chunhong, Song, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026163/
https://www.ncbi.nlm.nih.gov/pubmed/32066742
http://dx.doi.org/10.1038/s41467-020-14573-w