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The Ca(2+) permeation mechanism of the ryanodine receptor revealed by a multi-site ion model
Ryanodine receptors (RyR) are ion channels responsible for the release of Ca(2+) from the sarco/endoplasmic reticulum and play a crucial role in the precise control of Ca(2+) concentration in the cytosol. The detailed permeation mechanism of Ca(2+) through RyR is still elusive. By using molecular dy...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026163/ https://www.ncbi.nlm.nih.gov/pubmed/32066742 http://dx.doi.org/10.1038/s41467-020-14573-w |