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NF90 stabilizes cyclin E1 mRNA through phosphorylation of NF90-Ser382 by CDK2

Nuclear factor 90 (NF90), an RNA-binding protein, has been implicated in regulating interleukin-2 (IL-2) and the immune response. It was recently reported that NF90 is upregulated in hepatocellular carcinoma (HCC) tissues and promotes HCC proliferation through upregulating cyclin E1 at the posttrans...

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Detalles Bibliográficos
Autores principales: Ding, Donglin, Huang, Huixing, Li, Quanfu, Yu, Wenbo, Wang, Chenji, Ma, Haijie, Wu, Jiaxue, Dang, Yongjun, Yu, Long, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026180/
https://www.ncbi.nlm.nih.gov/pubmed/32123579
http://dx.doi.org/10.1038/s41420-020-0236-9