Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid

As quantitative analysis of biotherapeutics in cerebrospinal fluid (CSF) with LC-MS becomes increasingly widespread, there is a need for method developments towards higher sensitivity. By using artificial CSF (aCSF) in the development phase, the consumption of costly and sparsely available CSF can b...

Descripción completa

Detalles Bibliográficos
Autores principales: Fogh, Jens Rose, Jacobsen, Anne-Marie, Nguyen, Tam T. T. N., Rand, Kasper D., Olsen, Line Rørbæk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026242/
https://www.ncbi.nlm.nih.gov/pubmed/32008082
http://dx.doi.org/10.1007/s00216-020-02403-3

Ejemplares similares

Ejemplares similares