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Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells

After binding of its ligand transferrin, the transferrin receptor (TfR) is internalized via early endosomes. Ligand and receptor can be recycled. α-Taxilin was identified as an essential factor for TfR recycling. Apart from its role for iron uptake, TfR is a coreceptor for hepatitis C virus (HCV) in...

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Detalles Bibliográficos
Autores principales: Haberger, Vanessa, Elgner, Fabian, Roos, Jessica, Bender, Daniela, Hildt, Eberhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026371/
https://www.ncbi.nlm.nih.gov/pubmed/32117974
http://dx.doi.org/10.3389/fcell.2020.00044