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The role of control region mitochondrial DNA mutations in cardiovascular disease: stroke and myocardial infarction

Recent studies associated certain type of cardiovascular disease (CVD) with specific mitochondrial DNA (mtDNA) defects, mainly driven by the central role of mitochondria in cellular metabolism. Considering the importance of the control region (CR) on the regulation of the mtDNA gene expression, the...

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Detalles Bibliográficos
Autores principales: Umbria, Miriam, Ramos, Amanda, Aluja, Maria Pilar, Santos, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026394/
https://www.ncbi.nlm.nih.gov/pubmed/32066781
http://dx.doi.org/10.1038/s41598-020-59631-x