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Real-time cholesterol sorting in Plasmodium falciparum-erythrocytes as revealed by 3D label-free imaging

Cholesterol, a necessary component of animal cell membranes, is also needed by the lethal human malaria parasite Plasmodium falciparum. Because P. falciparum lacks a cholesterol synthesis pathway and malaria patients have low blood cholesterol, we speculated that it scavenges cholesterol from them i...

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Detalles Bibliográficos
Autores principales: Hayakawa, Eri H., Yamaguchi, Kentaro, Mori, Masahiro, Nardone, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026401/
https://www.ncbi.nlm.nih.gov/pubmed/32066816
http://dx.doi.org/10.1038/s41598-020-59552-9