In vitro replicative fitness of early Transmitted founder HIV-1 variants and sensitivity to Interferon alpha

Type I interferons, particularly interferon-alpha (IFN-α), play a vital role in the host's anti-viral defenses by interfering with viral replication. However, the virus rapidly evolves to exploit the IFN-α response for its replication, spread, and pathogenic function. In this study, we attempte...

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Detalles Bibliográficos
Autores principales: Ashok kumar, Manickam, Sonawane, Aanand, Sperk, Maike, Tripathy, Srikanth P., Neogi, Ujjwal, Hanna, Luke Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026412/
https://www.ncbi.nlm.nih.gov/pubmed/32066770
http://dx.doi.org/10.1038/s41598-020-59596-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026412/
https://www.ncbi.nlm.nih.gov/pubmed/32066770
http://dx.doi.org/10.1038/s41598-020-59596-x

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