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In vitro replicative fitness of early Transmitted founder HIV-1 variants and sensitivity to Interferon alpha
Type I interferons, particularly interferon-alpha (IFN-α), play a vital role in the host's anti-viral defenses by interfering with viral replication. However, the virus rapidly evolves to exploit the IFN-α response for its replication, spread, and pathogenic function. In this study, we attempte...
Autores principales: | Ashok kumar, Manickam, Sonawane, Aanand, Sperk, Maike, Tripathy, Srikanth P., Neogi, Ujjwal, Hanna, Luke Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026412/ https://www.ncbi.nlm.nih.gov/pubmed/32066770 http://dx.doi.org/10.1038/s41598-020-59596-x |
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