Genomic prediction of alcohol-related morbidity and mortality

While polygenic risk scores (PRS) have been shown to predict many diseases and risk factors, the potential of genomic prediction in harm caused by alcohol use has not yet been extensively studied. Here, we built a novel polygenic risk score of 1.1 million variants for alcohol consumption and studied...

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Detalles Bibliográficos
Autores principales: Kiiskinen, Tuomo, Mars, Nina J., Palviainen, Teemu, Koskela, Jukka, Rämö, Joel T., Ripatti, Pietari, Ruotsalainen, Sanni, Palotie, Aarno, Madden, Pamela A. F., Rose, Richard J., Kaprio, Jaakko, Salomaa, Veikko, Mäkelä, Pia, Havulinna, Aki S., Ripatti, Samuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026428/
https://www.ncbi.nlm.nih.gov/pubmed/32066667
http://dx.doi.org/10.1038/s41398-019-0676-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026428/
https://www.ncbi.nlm.nih.gov/pubmed/32066667
http://dx.doi.org/10.1038/s41398-019-0676-2

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