Laminin and Integrin in LAMA2-Related Congenital Muscular Dystrophy: From Disease to Therapeutics

Laminin-α2-related congenital muscular dystrophy (LAMA2-CMD) is a devastating neuromuscular disease caused by mutations in the LAMA2 gene. These mutations result in the complete absence or truncated expression of the laminin-α2 chain. The α2-chain is a major component of the laminin-211 and laminin-...

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Detalles Bibliográficos
Autores principales: Barraza-Flores, Pamela, Bates, Christina R., Oliveira-Santos, Ariany, Burkin, Dean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026472/
https://www.ncbi.nlm.nih.gov/pubmed/32116540
http://dx.doi.org/10.3389/fnmol.2020.00001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026472/
https://www.ncbi.nlm.nih.gov/pubmed/32116540
http://dx.doi.org/10.3389/fnmol.2020.00001

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