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Discovery of Multitarget-Directed Ligands Against Influenza A Virus From Compound Yizhihao Through a Predictive System for Compound-Protein Interactions

Influenza A virus (IAV) is a threat to public health due to its high mutation rate and resistance to existing drugs. In this investigation, 15 targets selected from an influenza virus–host interaction network were successfully constructed as a multitarget virtual screening system for new drug discov...

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Detalles Bibliográficos
Autores principales: Xu, Lvjie, Jiang, Wen, Jia, Hao, Zheng, Lishu, Xing, Jianguo, Liu, Ailin, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026480/
https://www.ncbi.nlm.nih.gov/pubmed/32117796
http://dx.doi.org/10.3389/fcimb.2020.00016