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Role of TG2-Mediated SERCA2 Serotonylation on Hypoxic Pulmonary Vein Remodeling

Sarco-endoplasmic reticulum Ca2+ ATPase (SERCA) pumps take up Ca2+ from the cytoplasm to maintain the balance of intracellular Ca2+. A decline in expression or activity of SERCA results in persistent store-operated calcium entry (SOCE). In cardiomyocytes as well as vascular smooth muscle cells (SMCs...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Wang, Dong, Luo, Erfei, Hou, Jiantong, Qiao, Yong, Yan, Gaoliang, Wang, Qingjie, Tang, Chengchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026497/
https://www.ncbi.nlm.nih.gov/pubmed/32116663
http://dx.doi.org/10.3389/fphar.2019.01611