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GABA(A) Receptor β(2)E155 Residue Located at the Agonist-Binding Site Is Involved in the Receptor Gating

GABA(A) receptors (GABA(A)Rs) play a crucial role in mediating inhibition in the adult brain. In spite of progress in describing (mainly) the static structures of this receptor, the molecular mechanisms underlying its activation remain unclear. It is known that in the α(1)β(2)γ(2L) receptors, the mu...

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Detalles Bibliográficos
Autores principales: Jatczak-Śliwa, Magdalena, Kisiel, Magdalena, Czyzewska, Marta Magdalena, Brodzki, Marek, Mozrzymas, Jerzy Władysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026498/
https://www.ncbi.nlm.nih.gov/pubmed/32116555
http://dx.doi.org/10.3389/fncel.2020.00002