Cargando…
GABA(A) Receptor β(2)E155 Residue Located at the Agonist-Binding Site Is Involved in the Receptor Gating
GABA(A) receptors (GABA(A)Rs) play a crucial role in mediating inhibition in the adult brain. In spite of progress in describing (mainly) the static structures of this receptor, the molecular mechanisms underlying its activation remain unclear. It is known that in the α(1)β(2)γ(2L) receptors, the mu...
Autores principales: | Jatczak-Śliwa, Magdalena, Kisiel, Magdalena, Czyzewska, Marta Magdalena, Brodzki, Marek, Mozrzymas, Jerzy Władysław |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026498/ https://www.ncbi.nlm.nih.gov/pubmed/32116555 http://dx.doi.org/10.3389/fncel.2020.00002 |
Ejemplares similares
-
Distinct Modulation of Spontaneous and GABA-Evoked Gating by Flurazepam Shapes Cross-Talk Between Agonist-Free and Liganded GABA(A) Receptor Activity
por: Jatczak-Śliwa, Magdalena, et al.
Publicado: (2018) -
GABA transient sets the susceptibility of mIPSCs to modulation by benzodiazepine receptor agonists in rat hippocampal neurons
por: Mozrzymas, Jerzy W, et al.
Publicado: (2007) -
α(1) Proline 277 Residues Regulate
GABA(A)R Gating through M2-M3 Loop Interaction in the Interface
Region
por: Kaczor, Przemyslaw T., et al.
Publicado: (2022) -
The Location of a Closed Channel Gate in the GABA(A) Receptor Channel
por: Bali, Moez, et al.
Publicado: (2007) -
Expression and Function of GABA Receptors in Myelinating Cells
por: Serrano-Regal, Mari Paz, et al.
Publicado: (2020)