Mutation in Fbxo11 Leads to Altered Immune Cell Content in Jeff Mouse Model of Otitis Media

The Jeff mouse mutant carries a mutation in the F-box only 11 gene (Fbxo11) and heterozygous animals display conductive deafness due to the development of otitis media (OM). The Fbxo11 locus is also associated with chronic otitis media with effusion (COME) and recurrent OM in humans. The Jeff mutati...

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Detalles Bibliográficos
Autores principales: Vikhe, Pratik P., Tateossian, Hilda, Bharj, Gurpreet, Brown, Steve D.M., Hood, Derek W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026503/
https://www.ncbi.nlm.nih.gov/pubmed/32117459
http://dx.doi.org/10.3389/fgene.2020.00050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026503/
https://www.ncbi.nlm.nih.gov/pubmed/32117459
http://dx.doi.org/10.3389/fgene.2020.00050

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