Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates

Genotoxicity testing is critical for predicting adverse effects of pharmaceutical, industrial, and environmental chemicals. The alkaline comet assay is an established method for detecting DNA strand breaks, however, the assay does not detect potentially carcinogenic bulky adducts that can arise when...

Descripción completa

Detalles Bibliográficos
Autores principales: Ngo, Le P, Owiti, Norah A, Swartz, Carol, Winters, John, Su, Yang, Ge, Jing, Xiong, Aoli, Han, Jongyoon, Recio, Leslie, Samson, Leona D, Engelward, Bevin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026589/
https://www.ncbi.nlm.nih.gov/pubmed/31822921
http://dx.doi.org/10.1093/nar/gkz1077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026589/
https://www.ncbi.nlm.nih.gov/pubmed/31822921
http://dx.doi.org/10.1093/nar/gkz1077

Ejemplares similares