Cargando…

Prevalence and architecture of posttranscriptionally impaired synonymous mutations in 8,320 genomes across 22 cancer types

Somatic synonymous mutations are one of the most frequent genetic variants occurring in the coding region of cancer genomes, while their contributions to cancer development remain largely unknown. To assess whether synonymous mutations involved in post-transcriptional regulation contribute to the ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Teng, Huajing, Wei, Wenqing, Li, Qinglan, Xue, Meiying, Shi, Xiaohui, Li, Xianfeng, Mao, Fengbiao, Sun, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026592/
https://www.ncbi.nlm.nih.gov/pubmed/31950163
http://dx.doi.org/10.1093/nar/gkaa019