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Quality controls induced by aberrant translation

During protein synthesis, translating ribosomes encounter many challenges imposed by various types of defective mRNAs that can lead to reduced cellular fitness and, in some cases, even threaten cell viability. Aberrant translation leads to activation of one of several quality control pathways depend...

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Detalles Bibliográficos
Autor principal: Inada, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026593/
https://www.ncbi.nlm.nih.gov/pubmed/31950154
http://dx.doi.org/10.1093/nar/gkz1201