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Quality controls induced by aberrant translation
During protein synthesis, translating ribosomes encounter many challenges imposed by various types of defective mRNAs that can lead to reduced cellular fitness and, in some cases, even threaten cell viability. Aberrant translation leads to activation of one of several quality control pathways depend...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026593/ https://www.ncbi.nlm.nih.gov/pubmed/31950154 http://dx.doi.org/10.1093/nar/gkz1201 |