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Composition and processing activity of a semi-recombinant holo U7 snRNP

In animal cells, replication-dependent histone pre-mRNAs are cleaved at the 3′ end by U7 snRNP consisting of two core components: a ∼60-nucleotide U7 snRNA and a ring of seven proteins, with Lsm10 and Lsm11 replacing the spliceosomal SmD1 and SmD2. Lsm11 interacts with FLASH and together they recrui...

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Detalles Bibliográficos
Autores principales: Bucholc, Katarzyna, Aik, Wei Shen, Yang, Xiao-cui, Wang, Kaituo, Zhou, Z Hong, Dadlez, Michał, Marzluff, William F, Tong, Liang, Dominski, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026596/
https://www.ncbi.nlm.nih.gov/pubmed/31819999
http://dx.doi.org/10.1093/nar/gkz1148