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Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes

G-quadruplex (G4) DNA structures are linked to key biological processes and human diseases. Small molecules that target specific G4 DNA structures and signal their presence would therefore be of great value as chemical research tools with potential to further advance towards diagnostic and therapeut...

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Detalles Bibliográficos
Autores principales: Kumar, Rajendra, Chand, Karam, Bhowmik, Sudipta, Das, Rabindra Nath, Bhattacharjee, Snehasish, Hedenström, Mattias, Chorell, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026600/
https://www.ncbi.nlm.nih.gov/pubmed/31912160
http://dx.doi.org/10.1093/nar/gkz1205