STRIDE—a fluorescence method for direct, specific in situ detection of individual single- or double-strand DNA breaks in fixed cells

We here describe a technique termed STRIDE (SensiTive Recognition of Individual DNA Ends), which enables highly sensitive, specific, direct in situ detection of single- or double-strand DNA breaks (sSTRIDE or dSTRIDE), in nuclei of single cells, using fluorescence microscopy. The sensitivity of STRI...

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Detalles Bibliográficos
Autores principales: Kordon, Magdalena M, Zarębski, Mirosław, Solarczyk, Kamil, Ma, Hanhui, Pederson, Thoru, Dobrucki, Jurek W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026605/
https://www.ncbi.nlm.nih.gov/pubmed/31832687
http://dx.doi.org/10.1093/nar/gkz1118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026605/
https://www.ncbi.nlm.nih.gov/pubmed/31832687
http://dx.doi.org/10.1093/nar/gkz1118

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