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Conformational ensembles of an RNA hairpin using molecular dynamics and sparse NMR data

Solution nuclear magnetic resonance (NMR) experiments allow RNA dynamics to be determined in an aqueous environment. However, when a limited number of peaks are assigned, it is difficult to obtain structural information. We here show a protocol based on the combination of experimental data (Nuclear...

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Detalles Bibliográficos
Autores principales: Reißer, Sabine, Zucchelli, Silvia, Gustincich, Stefano, Bussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026608/
https://www.ncbi.nlm.nih.gov/pubmed/31889193
http://dx.doi.org/10.1093/nar/gkz1184