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Conformational ensembles of an RNA hairpin using molecular dynamics and sparse NMR data
Solution nuclear magnetic resonance (NMR) experiments allow RNA dynamics to be determined in an aqueous environment. However, when a limited number of peaks are assigned, it is difficult to obtain structural information. We here show a protocol based on the combination of experimental data (Nuclear...
Autores principales: | Reißer, Sabine, Zucchelli, Silvia, Gustincich, Stefano, Bussi, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026608/ https://www.ncbi.nlm.nih.gov/pubmed/31889193 http://dx.doi.org/10.1093/nar/gkz1184 |
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