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Direct observation of damage clustering in irradiated DNA with atomic force microscopy

Ionizing radiation produces clustered DNA damage that contains two or more lesions in 10–20 bp. It is believed that the complexity of clustered damage (i.e., the number of lesions per damage site) is related to the biological severity of ionizing radiation. However, only simple clustered damage cont...

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Detalles Bibliográficos
Autores principales: Xu, Xu, Nakano, Toshiaki, Tsuda, Masataka, Kanamoto, Ryota, Hirayama, Ryoichi, Uzawa, Akiko, Ide, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026632/
https://www.ncbi.nlm.nih.gov/pubmed/31840169
http://dx.doi.org/10.1093/nar/gkz1159