Phosphorylation of Tet3 by cdk5 is critical for robust activation of BRN2 during neuronal differentiation

Tet3 regulates the dynamic balance between 5-methylcyotsine (5mC) and 5-hydroxymethylcytosine (5hmC) in DNA during brain development and homeostasis. However, it remains unclear how its functions are modulated in a context-dependent manner during neuronal differentiation. Here, we show that cyclin-d...

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Detalles Bibliográficos
Autores principales: Rao, Vinay Kumar, Swarnaseetha, Adusumalli, Tham, Guo-Hong, Lin, Wei-Qi, Han, Bin-Bin, Benoukraf, Touati, Xu, Guo-Liang, Ong, Chin-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026633/
https://www.ncbi.nlm.nih.gov/pubmed/31807777
http://dx.doi.org/10.1093/nar/gkz1144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026633/
https://www.ncbi.nlm.nih.gov/pubmed/31807777
http://dx.doi.org/10.1093/nar/gkz1144

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