Cargando…
Phosphorylation of Tet3 by cdk5 is critical for robust activation of BRN2 during neuronal differentiation
Tet3 regulates the dynamic balance between 5-methylcyotsine (5mC) and 5-hydroxymethylcytosine (5hmC) in DNA during brain development and homeostasis. However, it remains unclear how its functions are modulated in a context-dependent manner during neuronal differentiation. Here, we show that cyclin-d...
Autores principales: | Rao, Vinay Kumar, Swarnaseetha, Adusumalli, Tham, Guo-Hong, Lin, Wei-Qi, Han, Bin-Bin, Benoukraf, Touati, Xu, Guo-Liang, Ong, Chin-Tong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026633/ https://www.ncbi.nlm.nih.gov/pubmed/31807777 http://dx.doi.org/10.1093/nar/gkz1144 |
Ejemplares similares
-
CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation
por: Tellier, Michael, et al.
Publicado: (2020) -
Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA
por: Hashimoto, Hideharu, et al.
Publicado: (2015) -
A TetR-like regulator broadly affects the expressions of diverse genes in Mycobacterium smegmatis
por: Yang, Min, et al.
Publicado: (2012) -
FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function
por: Yang, Yeqing A., et al.
Publicado: (2016) -
CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progression
por: Park, Su Hyung, et al.
Publicado: (2014)