Cell-line specific RNA editing patterns in Trypanosoma brucei suggest a unique mechanism to generate protein variation in a system intolerant to genetic mutations

Trypanosoma brucei possesses a highly complex RNA editing system that uses guide RNAs to direct the insertion and deletion of uridines in mitochondrial mRNAs. These changes extensively alter the target mRNAs and can more than double them in length. Recently, analyses showed that several of the edite...

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Detalles Bibliográficos
Autores principales: Kirby, Laura E, Koslowsky, Donna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026638/
https://www.ncbi.nlm.nih.gov/pubmed/31840176
http://dx.doi.org/10.1093/nar/gkz1131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026638/
https://www.ncbi.nlm.nih.gov/pubmed/31840176
http://dx.doi.org/10.1093/nar/gkz1131

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