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Dynamics of the nucleosomal histone H3 N-terminal tail revealed by high precision single-molecule FRET

Chromatin compaction and gene accessibility are orchestrated by assembly and disassembly of nucleosomes. Although the disassembly process was widely studied, little is known about the structure and dynamics of the disordered histone tails, which play a pivotal role for nucleosome integrity. This is...

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Detalles Bibliográficos
Autores principales: Lehmann, Kathrin, Felekyan, Suren, Kühnemuth, Ralf, Dimura, Mykola, Tóth, Katalin, Seidel, Claus A M, Langowski, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026643/
https://www.ncbi.nlm.nih.gov/pubmed/31956896
http://dx.doi.org/10.1093/nar/gkz1186