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Accurate inference of the full base-pairing structure of RNA by deep mutational scanning and covariation-induced deviation of activity
Despite the large number of noncoding RNAs in human genome and their roles in many diseases include cancer, we know very little about them due to lack of structural clues. The centerpiece of the structural clues is the full RNA base-pairing structure of secondary and tertiary contacts that can be pr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026644/ https://www.ncbi.nlm.nih.gov/pubmed/31872260 http://dx.doi.org/10.1093/nar/gkz1192 |