Spatially multiplexed RNA in situ hybridization to reveal tumor heterogeneity

Multiplexed RNA in situ hybridization for the analysis of gene expression patterns plays an important role in investigating development and disease. Here, we present a method for multiplexed RNA-ISH to detect spatial tumor heterogeneity in tissue sections. We made use of a microfluidic chip to deliv...

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Detalles Bibliográficos
Autores principales: Voith von Voithenberg, Lena, Fomitcheva Khartchenko, Anna, Huber, Deborah, Schraml, Peter, Kaigala, Govind V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026647/
https://www.ncbi.nlm.nih.gov/pubmed/31853536
http://dx.doi.org/10.1093/nar/gkz1151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026647/
https://www.ncbi.nlm.nih.gov/pubmed/31853536
http://dx.doi.org/10.1093/nar/gkz1151

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